Inaugurating a New Era in Cancer Treatment—Intracellular Delivery

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By: Rakesh Gollen and Beata Sweryda-Krawiec

Rakesh GollenDrug delivery refers to approaches, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect. The ultimate goal of drug delivery research is to help patients by developing clinically useful formulations. In last few decades, many new strategies have been developed and used to treat cancer by improving or replacing conventional methods of drug delivery. Successful translation (from bench to bedside) of potential cancer and gene therapies largely depends on targeted drug delivery strategies. Continue reading

A Medicinal Homage to Trees on Arbor Day

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Apples come from trees, and as the old saying goes, “An apple a day keeps the doctor away.” As legend has it, Johnny Appleseed, a.k.a. John Chapman (no relation), planted apple orchards throughout much of the countryside during the 19th century. Much to the delight of pharmaceutical scientists are apples, since they are so rich in pectin, which is a widely used excipient. For many years, pectin’s effects on serum cholesterol have been noted, as well as its other utilities. Continue reading

Is Funding Subject to Gender Bias?

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By: David Warmflash

In recent discussions on federal government medical research funding, we noted that the National Institutes of Health (NIH) website compares funding versus disability and death burden in graphic form for a range categories of diseases.  It was noted that there is a loose correlation between money and disease burden, but that advocacy groups also have a major impact on how funding for a disease lines up vis-à-vis the relative burden of the disease on society. Considering this and other societal factors, can we say whether funding for medical research is sexist? Continue reading

Future and Advances of Nanotechnology Enabled Regenerative Therapy

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By: Rakesh Gollen and DILEEP R. JANAGAM

Rakesh Gollen

Regenerative therapy has evolved tremendously in recent years and is a promising approach in restoring the function of diseased, damaged, and aged tissues and organs. It is a highly interdisciplinary field that has been made possible by the intersection of recent advances in bioengineering, stem cell biology, and nanotechnology. Incorporation of nanotechnology allows better control over physical and biological properties of a biomaterial than conventional technologies.
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Building Your Professional Toolbox by Writing for a Blog

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By Amruta Indapurkar

When I was first approached by my colleague to write for the AAPS Blog, the first question that came to my mind was, “Why should I write a blog post?” and then I asked, “Even if I write a blog post, how it will benefit me?” So I started doing some research on this topic, and it was very surprising to know that writing blog posts can help people evolve to be better in every aspect of their lives. I thought it would be a good idea to share with you the reasons that motivated me to write my first blog post. Continue reading